The Four Corners region includes the arid western states of Arizona, Colorado, New Mexico and Utah. These four states have several common challenges to providing reliable water supplies including: rapid population growth, severe long term drought conditions and dwindling or overallocated natural water sources. Indirect potable reuse is currently being practiced in these states, often through managed groundwater replenishment or incidental means. Engineered potable reuse is viewed as the next step to maximizing utilization of this resource and building safe, reliable and resilient water resource portfolios. While steps are being taken toward DPR, each of these states faces challenges for implementing DPR. This panel discussion delves into the progress and issues regarding DPR in these four states.