This webinar will summarize the California Environmental Flows Framework and its application in the Los Angeles River. Across the country, state and local agencies are promoting water reuse and recycling to conserve water resources. Reuse and recycling of treated wastewater can result in a reduction of instream flow and can impact existing and future instream beneficial uses, setting up potential conflicts between policies aimed at promoting reuse, protecting water quality, and managing ecological resources. Agencies in California have come together to develop a statewide environmental flows framework that can be used to establish seasonal flow criteria. This framework is currently being applied in the Los Angeles River watershed to better evaluate the cumulative impacts of potential flow reductions associated with several water reuse and water capture projects. The Project will provide a science-based approach for assessing flow necessary to sustain beneficial uses. The Project outcomes will be used to help establish technically sound flow recommendations and evaluate the consequences of alternative flow scenarios for the LA River. This Project may also serve as a model for assessing similar situations in other river systems across the state.